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This EMS Xylene Substitute solution is specially designed for use in processing and staining histological/cytological specimens. It is essentially odorless with low toxicity, less irritating to the skin than xylene- and d-limonene-based clearants. It can be substituted for xylene and can be used with almost all tissue processors and automated slide stainers.
Most specimens may be processed with the same procedure used with xylene. If deparafinization is not complete, processing time may be increased.
While EMS Xylene Substitute will dry faster then D-limonene products, it will generally take longer than xylene. To accelerate this process, it is recommended that slides be allowed to stand on edge for 2-5 minutes to allow the solution to drain off. To ensure that all residual EMS Xylene Substitute is removed, tap edge of slide prior to coverslipping.
Note: Any EMS Xylene Substitute remains on the slide after coverslipping will dry completely without leaving any residue.
Do not use EMS Xylene Substitute with heat applications.
Use this EMS Xylene Substitute with a mounting medium that is compatible with xylene. The table below indicates compatibility of EMS Xylene-Subtitute with available mounting media. Failure to use a compatible mounting media may result in clouding of the specimens.
EMS Xylene Substitute is a flammable liquid and an aspiration hazard. May cause eyes, skin and respiratory tract irritation.
Storage: Store EMS Xylene Substitute at room temperature in a cool place
In extremely humid environments, EMS Xylene-Substitute may absorb moisture from the air. More frequent changes may be necessary.
Mounting Media |
EMS XyleneSubs
|
D-limonene
|
Xylenes
|
PROTOCOL SecureMount |
C
|
C
|
C
|
Richard Allen |
C
|
C
|
C
|
Coverbrand |
-
|
-
|
C
|
Fisher Permount |
C
|
C
|
C
|
Refrax |
C
|
C
|
C
|
Shandon Xylene Sub |
C
|
C
|
C
|
DPX |
C
|
C
|
C
|
PROTOCOL X&T |
C
|
C
|
C
|
Cytoseal |
NR
|
NR
|
C
|
Accumount 60 |
NR
|
NR
|
C
|
Acrytol |
NR
|
NR
|
C
|
Clearium |
NR
|
NR
|
C
|
Eukitt |
-
|
-
|
C
|
Flo-Texx |
-
|
-
|
C
|
Histomount |
-
|
-
|
C
|
Hypermount |
-
|
-
|
C
|
Permaslip |
-
|
-
|
C
|
Pro-Texx |
NR
|
NR
|
C
|
Shandon Mounting |
NR
|
NR
|
C
|
Stephens Substitute |
NR
|
NR
|
C
|
Micromount |
NR
|
NR
|
C
|
E-Z Mount |
NR
|
NR
|
C
|
C = Compatible NR = Not Recommended
EMS Xylene Substitute is available online from the EMS Catalog. For ordering or product information,